丙酸睾酮/庚酸睾酮/十一烯酸睾酮组成丙酸睾酮雄激素、合成代谢类固醇庚酸睾酮雄激素、合成代谢类固醇十一烯酸睾酮雄激素、合成代谢类固醇臨床資料商品名（英语：Drug nomenclature）Durasteron其他名稱TP/TE/TUe给药途径肌肉注射
丙酸睾酮/庚酸睾酮/十一烯酸睾酮，简称TP/TE/TUe，以商品名Durasteron出售，是丙酸睾酮（TP）、庚酸睾酮（TV）和十一烯酸睾酮（TUe）的注射複方藥，它们都是雄激素/合成代谢类固醇。[1][2]它是一种油溶液，含有20毫克TP、80毫克TE和150毫克TUe（总共250毫克睾酮酯和169.5毫克游离睾酮），并通过定期肌肉注射给药，例如每3或4周一次。[3][4][5]据报道，部分健美运动员使用Durasteron。[1][2]
参见[编辑]
丙酸睾酮/戊酸睾酮/十一烯酸睾酮
性激素复方制剂列表（英语：List of combined sex-hormonal preparations）
参考资料[编辑]
^ 1.0 1.1 Daher EF, Silva Júnior GB, Queiroz AL, Ramos LM, Santos SQ, Barreto DM, et al. Acute kidney injury due to anabolic steroid and vitamin supplement abuse: report of two cases and a literature review. International Urology and Nephrology. 2009, 41 (3): 717–23. PMID 19387860. S2CID 23319246. doi:10.1007/s11255-009-9571-8.
^ 2.0 2.1 Davani-Davari D, Karimzadeh I, Khalili H. The potential effects of anabolic-androgenic steroids and growth hormone as commonly used sport supplements on the kidney: a systematic review. BMC Nephrology. May 2019, 20 (1): 198. PMC 6545019 . PMID 31151420. doi:10.1186/s12882-019-1384-0 .
^ Joël, Charles A. Zur Behandlung männlicher Fertilitätsstörungen mit hohen Androgendosen [For the treatment of male fertility disorders with high androgen doses]. Gynecologic and Obstetric Investigation. 1960, 150 (3): 149–156. ISSN 1423-002X. doi:10.1159/000305737. [...] 20 mg Testosteronpropionat, 80 mg Testosteronheptanoat, 150 mg Testosteronundecylat (Durasteron Teva) [...]
^ Arends G, Zörnig H, Hager H, Frerichs G, Kern W. Hagers Handbuch der pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Drogisten, Ärzte u. Medizinalbeamte. Springer-Verlag. 14 December 2013: 1145–. ISBN 978-3-662-36329-4. At the same time, treatment with a long-acting testosterone preparation (Durasteron®) was instituted, with one injection given every four weeks.
^ Spitz IM, Hirsch HJ, Landau H, Zylber-Haran E, Gross V, Rachmilewitz EA. TSH secretion in thalassemia. Journal of Endocrinological Investigation. October 1984, 7 (5): 495–9. PMID 6439771. S2CID 20319052. doi:10.1007/BF03348456. The male patients were given a long acting tes- tosterone preparation (Durasteron, Teva) 250 mg by im injection every 3 weeks for a total of 8 injections.
查论编雄激素和抗雄激素激动药睾酮# · 双氢睾酮 · 氟羟甲基睾酮 · 甲二氢睾酮 · 甲睾酮 · 另见同化類固醇抗雄激素AR受体拮抗剂
甾体类: Abiraterone acetate +niraparib
Canrenone
Chlormadinone acetate
醋酸环丙孕酮
Delmadinone acetate
Dienogest
Drospirenone
Medrogestone
Megestrol acetate
Nomegestrol acetate
Osaterone acetate
Oxendolone
Potassium canrenoate
螺内酯
非甾体类: Apalutamide
比卡鲁胺
西咪替丁
Darolutamide
恩扎卢胺
氟他胺
Ketoconazole
Nilutamide
Seviteronel†
Topilutamide (fluridil)
类固醇生成抑制剂（英语：Steroidogenesis inhibitor）5α-还原酶（英语：5α-Reductase inhibitor）
Alfatradiol
Dutasteride
Epristeride
Finasteride
Saw palmetto extract
其它
Abiraterone acetate +niraparib
Aminoglutethimide
Bifluranol
醋酸环丙孕酮
氟他胺
Ketoconazole
Nilutamide
Seviteronel†
螺内酯
抗促性腺激素（英语：Antigonadotropin）
D2 receptor antagonists (prolactin releasers) (e.g., domperidone, 甲氧氯普胺, risperidone, haloperidol, 氯丙嗪, sulpiride)
Estrogens (e.g., bifluranol, 己烯雌酚, 雌二醇, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
GnRH agonists (e.g., leuprorelin)
GnRH antagonists (e.g., cetrorelix)
Progestogens (incl., chlormadinone acetate, 醋酸环丙孕酮, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)
其它
雄烯二酮免疫剂: Androvax (androstenedione albumin)
Ovandrotone albumin (Fecundin)
#世卫基本药物（WHO-EM）
‡从市场撤回
†臨床試驗第三階段
§臨床試驗未到第三階段
查论编雄激素受体AR (A, B)
兴奋剂: 1-雄烯二醇
1-睾酮
1-雄酮
4-雄烯二醇
4-Chlordehydromethyltestosterone
4-羟基睾酮
5-Androstenediol
5α-Androst-1-ene-3,17-dione
11-酮睾酮
17-((1-Oxoheptyl)oxy)androstan-3-one
17-((1-Oxopentyl)oxy)androstan-3-one
11β-甲基-19-去甲睾酮十二烷基碳酸酯
17-(1-Oxopropoxy)androstan-3-one
17β-Hydroxyandrost-2-ene-2-carbonitrile
19-去甲雄烯二醇
19-去甲雄烯二酮
11β-甲基-19-去甲睾酮（英语：11β-Methyl-19-nortestosterone）
十一酸二甲雄酮（英语：Dimethandrolone undecanoate）（DMAU）
19-Norandrosterone
19-Nordehydrotestosterone
肾上腺甾酮
雄异恶唑
雄诺龙
勃雄二醇
勃拉睾酮
勃拉嗪
勃地酮
19-去甲-4-雄烯二酮
勃来诺
勃金刚酯
卡普睾酮
氯司替勃
氯索睾酮
达那唑
去氧孕烯
去氧甲基睾酮
双氢睾酮
屈他雄酮
依奈替勃
环硫雄醇
乙炔睾酮
Ethyldienolone
乙雌烯醇
氟甲睾酮
甲酰勃龙
呋咱甲氢龙
Hexabolan
羟雄唑
左炔诺孕酮
美勃拉嗪
甲孕酮
美雄烷
麦酒宝龙
美雄诺龙
美睾酮
去氢甲睾酮/美雄酮
甲基异睾酮
Metenolone acetate
Metenolone enanthate
Methandriol
Methandriol propionate
Methasterone
Methylestrenolone
Methyltestosterone
Metribolone
Mibolerone
19-去甲睾酮（诺龙）
己酸诺龙
环戊丙酸诺龙
环己甲酸诺龙
环己丙酸诺龙
双环辛烯酸诺龙
癸酸诺龙
呋喃丙酸诺龙
对己氧苯丙酸诺龙
丁二酸诺龙
月桂酸诺龙
苯丙酸诺龙
丙酸诺龙
十一酸诺龙
诺勃酮
诺司替勃
诺乙雄龙
炔诺酮
炔诺孕酮
羟勃龙
Oxabolone cypionate
氧雄龙
奥生多龙
羟甲睾酮
羟甲烯龙
戊甲睾醇
普罗雄醇
奎勃龙
Quingestanol acetate
Roxibolone
Silandrone
Stanozolol
Stenbolone
Stenbolone acetate
Testolactone
睾酮
庚酸睾酮
十二酮酸睾酮
异戊酸睾酮
烟酸睾酮
丙酸睾酮
十一酸睾酮
THG
Thiomesterone
Tibolone
Tiomesterone
群勃龙
群勃龙醋酸酯
Trestolone
注意：此处包括了那些只有微弱男性化效应（或抗男性化（如氧雄龙））的蛋白同化甾类（因为它们合成代谢效应也是通过激活雄激素受体而是显得）。
Mixed (SARMs): AC-262,356
Andarine
BMS-564,929
Enobosarm
LGD-2226
LGD-3303
S-23
S-40503
拮抗剂: ARN-509
Benorterone
Bicalutamide
BMS-641,988
BOMT
Canrenoic acid
Canrenone
Chlormadinone acetate
西咪替丁
塞奥罗奈
Cyproterone
Cyproterone acetate
地仑雄酮
Dienogest
表睾酮
氟他胺
Galeterone
羟基氟他胺
己酸羟孕酮
Inocoterone
Ketoconazole
MDV3100
Megestrol acetate
Metogest
Mifepristone
Nilutamide
Nomegestrol
Nordinone
Norgestimate
Osaterone
Oxendolone
Potassium canrenoate
黄体酮
R2956
Rosterolone
螺内酯
Topterone
Zanoterone
酶(抑制剂)20,22-碳链裂解酶
22-ABC
3,3′-Dimethoxybenzidine
3-Methoxybenzidine
Aminoglutethimide
Cyanoketone
Danazol
Etomidate
Mitotane
Trilostane
17α-羟化酶，17,20-裂合酶
22-ABC
22-Oxime
Abiraterone
Bifonazole
Clotrimazole
Cyanoketone
Cyproterone acetate
Danazol
Econazole
Galeterone
Gestrinone
Isoconazole
Ketoconazole
L-39
Levonorgestrel
Liarozole
LY-207,320
MDL-27,302
Miconazole
Mifepristone
Orteronel
Pioglitazone
Rosiglitazone
Spironolactone
Stanozolol
SU-10,603
TGF-β
Tioconazole
Troglitazone
VN/87-1
YM116
3β-HSD (I, II)
4-MA
阿扎斯丁
腈酮
达那唑
环氧司坦
金雀异黄素
孕三烯酮
左炔诺孕酮
美替拉酮
羟甲
吡格列酮
罗格列酮
曲洛斯坦
曲格列酮
17β-HSD (I-XIV)
Danazol
Simvastatin
5α還原酶 (I, II)
22-Oxime
Alfatradiol
Azelaic acid
β-Sitosterol
Bexlosteride
Dutasteride
表睾酮
Epristeride
Finasteride
Izonsteride
L-39
Lapisteride
Polyunsaturated fatty acids (α-linolenic acid, linoleic acid, γ-linolenic acid, oleic acid)
Turosteride
Vitamin B6
锌
芳香酶
1,4,6-Androstatriene-3,17-dione
4-Androstene-3,6,17-trione
4-Cyclohexylaniline
4-Hydroxytestosterone
5α-DHNET
Abyssinone II
Aminoglutethimide
Anastrozole
抗坏血酸（维生素C）
Atamestane
Bifonazole
CGP-45,688
CGS-47,645
Clotrimazole
双氢睾酮
Difeconazole
Econazole
Exemestane
Fadrozole
Fenarimol
Finrozole
Formestane
Imazalil
Isoconazole
Ketoconazole
Letrozole
Liarozole
MEN-11066
Miconazole
Minamestane
Nimorazole
NKS01
ORG-33,201
Penconazole
Plomestane
Prochloraz
Propioconazole
Pyridoglutethimide
Rogletimide
Rotenone
Talarozole
Testolactone
Tioconazole
Triadimefon
Triadimenol
Troglitazone
Vorozole
YM511
锌
Note: 21-Hydroxylase inhibitors may also affect androgen levels as they prevent metabolism of androgen steroid precursors.
其他内源
雄激素: 双氢睾酮
睾酮
抗雄激素: 表睾酮
前体: 胆固醇
22R-羟胆固醇
20α,22R-羟胆固醇
孕烯醇酮
17-羟基孕烯醇酮
黄体酮
17-羟孕酮
Cortodoxone/Deoxycortisol
脱氢表雄酮
硫酸脱氢表雄酮
雄烯二醇
雄烯二酮
间接
Estrogens/Antiestrogens (see here)
GnRH agonists/antagonists (see here)
Gonadotropins/Antigonadotropins (see here)
Plasma proteins (SHBG, ABP, Albumin)
Progestogens/Antiprogestins (see here)
Prolactin
操作
肾上腺切除术
垂体切除术
卵巢切除术
睾丸切除术